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Peptic Ulcer Disease Deaths

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Peptic ulcers are ulcers (sores) which occur inside the upper part of the alimentary (gastrointestinal) tract. They can develop in the lower part of the oesophagus (gullet), stomach, its end (the pylorus), the next bit (the duodenum) and as far down as the jejunum (the first parts of the small intestine). These are all places that gastric (stomach) juices can get to. These juices contain hydrochloric acid and digestive enzymes (pepsin). The most common peptic ulcers are found in the duodenum. Most duodenal ulcers are caused by the presence of a bacteria (Helicobacter pylori). Gastric ulcers are more common in people who are poor and undernourished, and in chronic users of aspirin (and other non-steroidal anti-inflammatory drugs - NSAIDs) and alcohol. Duodenal ulcers particularly affect men aged 20 to 50 years, and gastric ulcers men aged 40 to 70 years.

Peptic ulcers can cause pain, bleed (sometimes fatally), perforate (often fatally) and cause strictures (stenosis), a narrowing that prevents some or all food getting through.

Peptic ulcer disease caused 0.46% of all deaths worldwide in 2002, an average of 42 deaths per million people per year.

International Classification of Diseases-10 codes: K25-K27,

Territories are sized in proportion to the absolute number of people who died from peptic-ulcer disease in one year.


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